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Endoscopic submucosal dissection (ESD) is considered a curative therapy for selected early gastric cancer (EGC) in high-incidence populations. However, there is a small but substantial rate of residual, recurrent, synchronous, and metachronous cancer after ESD. Endoscopic surveillance is recommended to detect these lesions, but the optimal interval and duration of surveillance is not well established.
To address this issue, investigators in Korea retrospectively reviewed the records of 1347 EGC patients treated with curative ESD in a large teaching hospital during a 7-year period. Routine surveillance endoscopy was performed at 3, 6, 12, 18, and 24 months, and then annually. Residual disease or local recurrence (found at a prior site within …