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Following relatively recent advances in the diagnosis, treatment, and prevention of infection due to Taenia solium, a well-funded multinational group sought to affect the transmission of this infection in a highly endemic area in northern Peru. The study's interventions involved both humans and pigs to maximize the likelihood of success in achieving transmission elimination. Outcomes were measured in pigs only, because of potential latency of clinical manifestations in human infection and the overall low prevalence of taeniasis. The researchers used serology and necropsy to identify pigs with live, nondegenerated cysts that could be responsible for infection transmission.
The study was conducted in three phases. Phase 1 included pig replacem…