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Use of intrauterine contraception is rising in the U.S., but uptake would be further improved with more information about the available options. In a 7-year international study evaluating the safety and efficacy of the 52-mg levonorgestrel-releasing intrauterine device (LNG-IUD; marketed in the U.S. as Mirena and Liletta) compared with the copper IUD (TCu380A), WHO researchers randomized 1884 users to the LNG-IUD and 1871 users to the TCu380A (mean overall age, 30). During each year of follow-up, the 52-mg LNG-IUD was more effective than the TCu380A. Although only 398 LNG-IUD users completed 7 years of follow-up, no pregnancies were reported between years 5 and 7, producing a cumulative failure rate of 0.53% at 7 years (compared with 0.12% …