Neurologic Manifestations of Acute HIV Infection

In a Thai study, more than half of patients with acute HIV disease had objective neurologic findings.

Neurologic disease has long been recognized as a manifestation of all stages of HIV infection; still, the rates and characteristics of neurologic findings in acute HIV infection have not been well defined. Now, investigators in Thailand have conducted a prospective neurologic and neuropsychologic assessment of a cohort of patients with acute HIV disease identified between 2009 and 2014. Participants were followed from study entry (when the presence of acute infection was identified) through 12 weeks of combination antiretroviral therapy; 139 of 197 patients had complete neurologic data.

The cohort was 93% male, with mean estimated duration of HIV infection at study entry of 19 days. One or more neurologic findings were identified in 53% of p…

Reviewing Author

Richard T. Ellison III, MD

Disclosures

Consult/Advisory BoardAcurx Pharmaceuticals, LLC;

Grant/Research SupportDoctors Company Foundation, Massachusetts Department of Public Health

Richard T. Ellison III, MD

Disclosures

Consult/Advisory BoardAcurx Pharmaceuticals, LLC;

Grant/Research SupportDoctors Company Foundation, Massachusetts Department of Public Health

Neurologic Manifestations of Acute HIV Infection

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Reviewing Author