Neurologic Signs and Symptoms Associated with Acute HIV Infection

Patients with acute, previously undiagnosed HIV infection often present with neurologic complaints.

To characterize neurological findings in patients with acute HIV infection, researchers reviewed data from a high-risk population in Thailand (the Southeast Asia Research Collaboration with the University of Hawaii [SEARCH] cohort) between 2009 and 2014. Of 236 cases of acute HIV infection identified, 197 were enrolled in the study and 139 (93% men) had complete neurologic data.

After initial assessments, patients were started on a combination antiretroviral therapy regimen (cART) with or without antiretrovirals; 94% initiated therapy within 3 days of diagnosis. HIV-trained physicians conducted structured neurologic interviews and examinations at study entry and at 4 and 12 weeks after cART was started.

A total of 245 neurologic findings were…

Reviewing Author

Jennifer L. Wiler, MD, MBA, FACEP

Disclosures

Leadership Positions in Professional SocietiesColorado Medical Society (Member, Board of Directors)

Jennifer L. Wiler, MD, MBA, FACEP

Disclosures

Leadership Positions in Professional SocietiesColorado Medical Society (Member, Board of Directors)

Neurologic Signs and Symptoms Associated with Acute HIV Infection

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Reviewing Author