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One of the problems with implementation of paradigms like “resect and discard” has been that endoscopic predictions of histology show significant interobserver variation. Automated systems based on computer-aided detection or other technologies could possibly solve this problem.
Two such systems are described in two recent studies. One uses endocytoscopy and narrowband imaging. In a validation study, this system produced high-confidence diagnoses (neoplastic vs. non-neoplastic) in 65% of cases with accuracies >95% with high confidence. For example, for diagnosis of adenomatous lesions with high confidence, sensitivity was 97.6%, specificity was 95.8%, accuracy was 96.9%, positive-predictive value was 97.6%, and negative-predictive value was …