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Despite advances in the care of peptic ulcer disease (PUD), mortality in hospitalized PUD patients has not changed significantly, and details of long-term mortality in these patients remain unclear. Investigators used Finnish health databases to identify 8146 patients hospitalized with PUD between 2000 and 2008 and evaluated mortality and cause of death in these patients during a mean 4.9 years of follow-up (40,200 patient-years).
Overall mortality was higher in patients with PUD than in the standard population (standardized mortality ratio, 2.53; 95% confidence interval, 2.44–2.63). Almost 12% of the patients died within 1 year; there was no change in the death rate over the study period. Patients with complicated (bleeding, perforated) ulc…