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Several states have enacted laws requiring adherence to the original FDA-approved regimen for abortion with mifepristone and misoprostol (600-mg oral mifepristone followed by 400-µg oral misoprostol in a clinician's office). Although clinical trials were initially conducted using this regimen (originally approved in 2000), the FDA recently updated its labeling to align with endorsements by the WHO and the American College of Obstetricians and Gynecologists of an evidence-based regimen that is more effective and better tolerated (200-mg oral mifepristone followed by 800-µg buccal misoprostol at home). To understand the impact of a 2011 Ohio law mandating use of the original FDA-approved regimen, investigators assessed the outcomes of medicat…