Douching was associated with almost twofold higher risk for ovarian cancer.
Douching remains prevalent among U.S. women (especially black women) despite associations with adverse reproductive health outcomes, including pelvic inflammatory disease and ectopic pregnancy. In a prospective cohort study, investigators asked whether douching or genital talc use predicts risk for ovarian cancer in a cohort of some 50,000 women, each of whom had a sister with breast cancer.
After a median follow-up of 7 years, 154 women received diagnoses of ovarian cancer. Women who reported douching at baseline had significantly higher risk for ovarian cancer (hazard ratio, 1.8). Talc use was not associated with subsequent development of ovarian cancer.
Reviewing Author
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)