Infective Endocarditis After TAVR: An Underestimated Problem

Infective endocarditis after transcatheter aortic-valve replacement is associated with high mortality in a large observational study.

Few studies have focused on factors associated with infective endocarditis after transcatheter aortic-valve replacement (TAVR) procedures. Now, researchers have analyzed registry data on 250 patients experiencing infective endocarditis out of approximately 20,000 TAVR patients from 47 centers.

Overall, endocarditis incidence was 1.1% per person-year. The median time from the procedure to onset of an endocarditis symptom was 5.3 months. Higher risks for developing infective endocarditis after TAVR were associated with male sex (hazard ratio, 1.69), diabetes mellitus (HR, 1.52), and moderate-to-severe aortic regurgitation (HR, 2.05); older age was associated with lower risk (HR, 0.97 per additional year). The most frequently observed microorga…

Reviewing Author

Pascal Meier, MD

Disclosures

Editorial BoardsOpen Heart

Leadership Positions in Professional SocietiesEuropean Society of Cardiology (Communication Committee); European Association of Percutaneous Cardiovascular Interventions (Chair, Web & Communication Committee)

Pascal Meier, MD

Disclosures

Editorial BoardsOpen Heart

Infective Endocarditis After TAVR: An Underestimated Problem

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Reviewing Author