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Most guidelines recommend that patients with nonvariceal upper gastrointestinal bleeding (UGIB) undergo endoscopy within 24 hours of presentation. But whether earlier endoscopy is associated with improved outcomes is unclear.
To examine this issue, investigators at a single academic medical center retrospectively reviewed the records of 361 patients with acute nonvariceal UGIB and compared outcomes between those who received standard endoscopy (SE) within 24 hours and those who received urgent endoscopy (UE) within 12 hours; 25% of patients received UE.
Overall, 10% of patients met the primary endpoint of inpatient mortality, rebleeding, or the need for additional endoscopic, surgical, or radiographic intervention. In a multivariate analysis,…