Best Practices in Diagnosis and Management of Barrett Esophagus with Low-Grade Dysplasia

A clinical practice update based on best available evidence and expert opinion

Sponsoring Organization: American Gastroenterological Association (AGA)

Target Audience: Gastroenterologists

Target Population: Patients diagnosed with Barrett esophagus–associated low-grade dysplasia

Background and Objective: There is increasing clarity on best practices for endoscopic management of Barrett esophagus (BE) with high-grade dysplasia but less clear direction on diagnosis and management of BE with low-grade dysplasia (LGD). This expert review provides best practice recommendations based on current evidence and expert opinion.

Key Recommendations

BE should be defined by a standardized system (Prague classification) with specifics on visible lesions.
LGD histologic diagnosis needs confirmation by a recognized expert pathologist.
Expert…

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors