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Very-low-birth-weight (VLBW) infants have lower morbidity and improved neurodevelopmental outcomes when fed their mother's milk compared to a preterm infant formula. When a mother of a VLBW preterm infant cannot provide enough of her own milk, supplemental human donor milk is available in some communities. Currently, there are 22 donor-milk banks in the U.S.
To assess whether supplemental donor milk improves outcomes, researchers randomized 363 VLBW infants in four neonatal units in Canada to be fed nutrient-enriched donor milk or a preterm formula when their mother's milk was not available. Mean birth weight was 996 g and mean gestational age was 27.7 weeks. More than one quarter of babies in both groups were exclusively fed maternal milk, …