Compared with unvaccinated women, HPV vaccine recipients had lower prevalence of HPV 6 years after immunization, but coverage is still inadequate.
Despite recommendations for universal immunization against human papillomavirus (HPV) during adolescence, the U.S. lags woefully in coverage. To assess the direct and indirect effects of HPV vaccination, investigators conducted a prospective study of National Health and Nutrition Examination Survey data from some 2300 women aged 18 to 29. Data from the prevaccine period (2003–2004) versus the postvaccine period (2007–2012) were analyzed.
Among women who received at least one dose of vaccine, prevalence of any of the four HPV types included in the vaccine fell from 10% to 4% (P=0.003), but no change in nonvaccine-type HPV was observed. Among unvaccinated women, no change in prevalence of any HPV type was observed. During 2011 and 2012, only 3…
Reviewing Author
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)
DisclosuresConsultant/Advisory BoardAicuris; Bayer; GSK; Innovative Molecules; Merck; MAPP Biopharmaceutical (Safety Monitoring Committee)
RoyaltiesUpToDate
Grant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; GSK; Moderna; Assembly Biomedical; Aicuris
Editorial BoardsSexually Transmitted Diseases; Sexually Transmitted Infections; Journal of Infectious Diseases
Leadership PositionsID Division Chiefs Community of Practice (At-Large Member)