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Studies on canine detection of human cancers have been impressive for lung, breast, melanoma, ovarian, prostate, and colon cancers. It is thought that cancers produce volatile organic compounds that should be subject to detection by canine or lab testing. Accordingly, there has been a tremendous interest in the development of the “electronic nose” (e-nose).
This proof-of-concept study used an e-nose (Aeonose, The eNose Company, Zutphen, Netherlands), which employed chemical-to-electrical interfaces to measure subtle differences in volatile compounds in health and disease. The device uses a machine learning platform/neural network to discriminate specific diseases. One hundred and twenty-eight patients with a history of dysplastic Barrett eso…