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The search continues for nonpharmacological treatments for pediatric depression that are effective and maintain benefits a year posttreatment. These investigators conducted a multisite, pragmatic trial comparing three interventions in England.
The 465 participants (age range, 11–17 years) had been comprehensively diagnosed with major depression and were randomized to receive:
20 sessions of cognitive-behavioral therapy (CBT),
28 sessions of psychoanalytic therapy, or
12 sessions of a psychosocial intervention.
The psychosocial intervention involved psychoeducation, behavioral activation, and problem solving. Randomization was stratified by age (11–13, 14–15, and 16–17), sex, geographic region, and depression severity. Specialty physicians or nur…