Diagnosis of Tuberculosis in Adults and Children

Recommendations on TB testing incorporate recent evidence on using an interferon-gamma release assay for latent TB and nucleic acid amplification testing for active TB.

Target Population: Clinicians, laboratory workers, staff in medical offices, academic training programs, medical schools, and others involved in the management of patients with latent or suspected tuberculosis (TB)

Sponsoring Organizations: American Thoracic Society, Infectious Diseases Society of America, Centers for Disease Control and Prevention

Background and Objective

These evidence-based consensus guidelines were formulated using the Grading, Recommendations, Assessment, Development, and Evaluation (GRADE) approach.

Key Points

TB is a leading cause of infectious disease morbidity and mortality worldwide but, unfortunately, has many diagnostic uncertainties.
For testing an individual suspected of having latent TB infection, an interferon-gam…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection