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Ohayon and colleagues reexamined the prevalence in the general population of restless legs syndrome (RLS) using DSM-5 criteria but applying the frequency and duration of symptoms to the case definition. They contacted 19,136 noninstitutionalized U.S. persons older than 18 years via a cross-sectional telephone survey; 17% chose not to participate. Participants were asked about leg symptoms, impairment, psychiatric and medical conditions, medications and substance use, and health-related quality of life. Analysis used two different weekly frequency thresholds.
When using 1 day/week of symptoms as the criterion for RLS, prevalence ranged from 5.7% to 12.3%. Using a 3-day/week symptomatic criterion, the prevalence dropped to between 1.8% and 4.5…