Randomized trial data suggest that high-flow oxygen is effective as rescue therapy after standard oxygen therapy fails.
The use of high-flow warm humidified oxygen (HFWHO) in children with bronchiolitis is becoming more frequent despite an absence of supporting data from randomized trials.
In a three-year, single-center trial, investigators compared the time to weaning off oxygen among 202 children aged <24 months with moderate symptoms of bronchiolitis who were randomized to HFWHO or standard nasal cannula oxygen therapy upon admission to the hospital or presentation to the emergency department.
Time to weaning off oxygen was similar between groups. Significantly more children in the standard therapy group than in the HFWHO group failed treatment (33 vs. 14). Of the 33 children who failed standard therapy, 20 responded to HFWHO and did not require treatment e…
Reviewing Author
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)
DisclosuresGrant/Research SupportNIH Institutional Clinical and Translational Science Award; Agency for Healthcare Research and Quality National Center for Pediatric Practice Based Research Learning; Patient-Centered Outcomes Research Institute
Editorial BoardsCurrent Problems in Pediatric Adolescent Healthcare
Leadership Positions in Professional Societies College of Physicians of Philadelphia (Board of Trustees)