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Diabetic polyneuropathy (DPN) is one of the most common complications in patients with type 2 diabetes mellitus, affecting about 30% of patients admitted to hospitals and 20% to 30% of community-based patients. Risk factors include diabetes duration, hyperglycemia, and age, as well as hypertension, dyslipidemia, and obesity (Rev Diabetic Stud 2015; 12:48). The role of glycemic variability in DPN has been unclear. To see if the variations in fasting plasma glucose (FPG), measured by the coefficient of variation (CV), could predict DPN risk independently of glycated hemoglobin (HbA1c) and other risk factors, researchers enrolled 36,152 patients ≥30 years old with type 2 diabetes in the Diabetes Care Management program of Taiwan.
During an aver…