Is Coffee a Potential Therapy for Nonalcoholic Fatty Liver Disease?

Coffee consumption is suggested to decrease risk for liver disease and improve liver-related outcomes in patients with chronic hepatitis C virus (HCV) infection, likely via reduction in oxidative stress. Limited data point to similar findings in nonalcoholic fatty liver disease (NAFLD).

To evaluate the association between coffee consumption and chronic liver disease with and without cirrhosis by liver disease etiology, investigators conducted a nested case-control study involving 95,197 Medicare fee-for-service participants who completed a standardized questionnaire on coffee consumption as part of a larger cohort study. Liver disease status was identified using Medicare claims data. Case and control patients were matched by age, sex, ethnic…