Bacteremia with Encapsulated Pathogens May Indicate Primary Immunodeficiency

Primary immunodeficiencies were found in 19% of young adults who suffered from such infections but did not have a predisposing condition.

Primary immunodeficiencies (PIDs), such as complement disorders and various forms of antibody deficiencies, are known to predispose affected individuals to infections with encapsulated pathogens, including Streptococcus pneumoniae (SP), Neisseria meningitidis (NM), Neisseria gonorrhoeae (NG), Haemophilus influenzae (HI), and group A Streptococcus (GAS). However, patients with PIDs may not become symptomatic until adulthood.

To investigate the prevalence of PIDs among young adults in the absence of predisposing factors, French researchers conducted a retrospective study involving patients 18 to 40 years of age with SP, NM, NG, HI, or GAS invasive infections. Patients were identified from discharge and microbiology laboratory databases in thre…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Bacteremia with Encapsulated Pathogens May Indicate Primary Immunodeficiency

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Reviewing Author