Loading...
Patients commonly receive advice about their body weight, and fluctuations in weight are a typical occurrence for many people as they cycle through various diets. To examine the relationship between weight fluctuations and risks for cardiovascular events, investigators in a manufacturer-funded study analyzed data on 9509 people from the Treating to New Targets (TNT) trial, which tested atorvastatin in patients with established coronary artery disease.
The authors defined body-weight fluctuations as intraindividual variability in weight between study visits, which occurred every 3 months in the first year and every 6 months thereafter. Mean baseline weight was 85 kg. During a median follow-up of 4.7 years, participants had a median of 12 weig…