Late-Life Mentally Stimulating Activities and Incident Mild Cognitive Impairment

Mentally stimulating activities may decrease the risk for mild cognitive impairment in late life.

To evaluate the effect of late-life mentally stimulating activities on the incidence of mild cognitive impairment (MCI), researchers conducted a longitudinal, population-based study. The 1929 participants (median age, 77) completed a questionnaire about mentally stimulating activities within 1 year of enrollment. Neuropsychological testing was performed at baseline and every 15 months. Cognitive status was determined by an expert consensus panel. Apolipoprotein E ℇ4 status was also obtained.

Of the participants, 512 were apolipoprotein E ℇ4 carriers, and 456 developed MCI during about 4 years of follow-up. After adjustment for age, sex, and education, mentally stimulating activities performed at least 1 to 2 times a week were associated with…

Reviewing Author

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Late-Life Mentally Stimulating Activities and Incident Mild Cognitive Impairment

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Reviewing Author