Which PTSD Treatment for Which Sort of Trauma History?

A history of sexual trauma predicts a more robust therapeutic response to interpersonal therapy in post-traumatic stress disorder.

Information about treatment moderators or predictors of treatment response can be used to match patients to particular therapies. Whereas prolonged exposure therapy (PE) is commonly used for post-traumatic stress disorder (PTSD), interpersonal psychotherapy (IPT) has only recently been shown to be effective; relaxation therapy (RT) may provide some benefit, with generally weaker effects. In a previous trial (NEJM JW Psychiatry Apr 2015 and Am J Psychiatry 2015; 172:430), IPT had similar reductions in clinician-rated PTSD symptoms as PE and nonsignificantly lower dropout; IPT and PE had better results than RT. In a planned secondary analysis, investigators have examined whether clinician-recorded interpersonal trauma (i.e., not impersonal tr…

Reviewing Author

Claire Wilcox, MD

Disclosures

EquityMannkind Corporation

Grant/Research SupportNIH

Claire Wilcox, MD

Disclosures

EquityMannkind Corporation

Grant/Research SupportNIH

Which PTSD Treatment for Which Sort of Trauma History?

Topics

Reviewing Author