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Target Audience: Primary care clinicians
The incidence of diagnosed thyroid cancer in the U.S. has increased threefold during the past 20 years, but thyroid cancer–related mortality has barely changed during that time. In South Korea, where a widespread program of ultrasound screening for thyroid cancer was launched in the late 1990s, the situation has been even more dramatic, with a 15-fold increase in diagnoses, no change in thyroid cancer–related mortality, and a substantial rise in surgical complications, including vocal cord paralysis and hypoparathyroidism.
In 1996, the USPSTF recommended against screening for thyroid cancer in asymptomatic patients; this 201…