Describing Esophagogastric Junction Outflow Obstruction and Hypercontractile Esophagus

A small retrospective study provides some natural history data.

The Chicago classification defined esophagogastric junction outflow obstruction (EGJOO) and hypercontractile esophagus (HE) as major esophageal motility disorders. However, the association of these manometric findings with longitudinal outcomes of symptom burden is not well defined.

In a retrospective study, investigators reviewed outcomes in 56 patients with EGJOO, 40 with HE, and 33 with normal findings (controls) as determined by high-resolution impedance manometry. At presentation, compared with controls, the EGJOO group had higher rates of dysphagia and opiate use, and the HE group had higher prevalence of chest pain. There were no significant differences in structural abnormalities evident by endoscopy or esophagram) between groups.

In …

Reviewing Author

David A. Johnson, MD

Disclosures

Consultant/Advisory boardMedscape/WebMD; Pfizer; CRH Medical Corporation; Aries

EquityCRH Medical Corporation

Editorial boardsMedscape Gastroenterology

Leadership positions in professional societiesAmerican College of Gastroenterology Research Institute Board of Directors