Rapid Eye Movement Sleep: Another Link in the Sleep–Dementia Connection

REM sleep abnormalities may increase the risk for dementia.

Sleep disturbances have been examined recently as a potential risk factor for dementia. In this study, investigators analyzed whether objective sleep abnormalities in 321 participants from the Framingham Offspring Study were associated with increased dementia risk. Sleep measurements were conducted by home-based polysomnography. Incident dementia was adjudicated by a study dementia review committee.

Dementia was diagnosed in 32 participants during a mean follow-up of 12 years. Of these, 24 met criteria for Alzheimer disease (AD) dementia. Lower rapid eye movement (REM) sleep percentage and longer REM latency were associated with increased risk for all-cause dementia. A 1% reduction in REM sleep was associated with a 9% increase in dementia r…

Reviewing Author

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Jennifer Rose V. Molano, MD

Disclosures

Grant/Research SupportNational Center for Advancing Translational Science – Cincinnati Center for Clinical and Translational Science and Training

Editorial BoardsBrain & Life

Rapid Eye Movement Sleep: Another Link in the Sleep–Dementia Connection

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Reviewing Author