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Because medications for bipolar depression are often ineffective and frequently produce adverse effects, nonpharmacological approaches hold great interest. Morning light in patients with bipolar depression has had mixed results and induces occasional hypomania. Based on preliminary work, investigators conducted a randomized, 6-week study comparing midday broad-spectrum bright-light therapy (7000 lux) with dim red light (a “sham” condition; 50 lux).
The 43 participants had moderate levels of bipolar depression with no manic symptoms and were on stable medications (mean age, 45; 67% female); 67% had bipolar I disorder, and 83% had some seasonality. Exclusions included manic, hypomanic, or mixed episodes within 6 months; rapid cycling in the pa…