After an acute myocardial infarction, nonadherence to beta-blockers was not associated with worsened mortality.
Patient nonadherence to drug regimens is widely decried, but the clinical implications of not taking prescribed medications is not well understood. Studying nonadherence may provide some insight into whether certain drugs, in everyday practice, are providing a benefit. To examine adherence rates among patients who had suffered an acute myocardial infarction (AMI), investigators made use of the Medicare Chronic Condition Data Warehouse files from 2007 to 2011.
The approximately 91,000 patients had all received three therapies — angiotensin-converting enzyme (ACE) inhibitors/angiotensin receptor blockers (ARBs), statins, and beta-blockers — within 30 days of hospital discharge. Adherence rates were derived from prescription fill information. N…
Reviewing Author
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association