Yellow Fever Virus Detected in Urine and Semen

Urine and semen tested positive for yellow fever virus, whereas serum tested negative, in a patient with acute symptoms during a recent outbreak in Brazil.

Yellow fever (YF) outbreaks continue to erupt in South America and Africa, despite the availability of a highly effective vaccine. YF infection is confirmed by detection of virus RNA in the blood and recently by detection in urine (J Clin Microbiol Nov 2017; 55:3294).

Investigators now present a case report of YF virus detection in the urine and semen of a 65-year-old man unvaccinated against YF who developed acute YF and associated severe thrombocytopenia during a recent outbreak in Brazil, in which 792 confirmed cases and 274 deaths were identified as of July 2017.

Three weeks after symptom onset, samples of the patient's serum, urine, and semen were tested for YF virus using standard and quantitative reverse transcription polymerase chain …

Reviewing Author

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Mary E. Wilson, MD

Disclosures

Consultant/Advisory BoardOneHealthTrust (formerly Center for Disease Dynamics, Economics, and Policy); Global Health Institute, University of Wisconsin

RoyaltiesUpToDate

Editorial BoardsJournal of Travel Medicine

Yellow Fever Virus Detected in Urine and Semen

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Reviewing Author