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Using a mathematical prediction model, investigators evaluated the cost effectiveness of four strategies for administering influenza vaccine to a hypothetical cohort of children at a tertiary pediatric emergency department (ED). The strategies were to offer vaccine to (1) all patients, (2) only patients <5 years of age, (3) only high-risk patients, or (4) no patients.
Offering influenza vaccine to all patients was the most cost-effective strategy, with a net societal cost of US$104 per patient or $114 per influenza case avoided. Compared with offering vaccine to no patients, offering to all yielded the following results:
Savings of $34 per influenza case avoided
Incremental cost-effectiveness ratio per case averted of $1,030
27 fewer influenza …