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As the quest to cure dementia continues, lifestyle modification is an emerging strategy to prevent or modify the dementia process. With the number of individuals with dementia expected to increase from 47 million in 2015 to 66 million by 2030, preventing or delaying the onset of dementia may reduce the global burden. One third of risk factors for dementia are potentially modifiable, including education in early life; hearing loss, hypertension, and obesity in midlife (45–65 years); and smoking, depression, physical activity, social engagement, and diabetes mellitus in late life (>65 years) (NEJM JW Neurol Oct 2017 and Lancet 2017 Jul 19; [e-pub]).
Longitudinal studies have provided intriguing results on the…