Many Methods to Prevent Cognitive Decline Fall Short

A series of systematic reviews commissioned by the National Institute on Aging evaluated the association between various interventions and prevention of cognitive decline, mild cognitive impairment (MCI), or Alzheimer dementia. Findings were as follows:

Physical activity (16 trials): There was insufficient evidence that single-component physical activity (aerobic training, resistance training, or tai chi) prevents cognitive decline and dementia in initially nondemented adults. In four trials, physical activity with multiple components that included flexibility, strength training, balance, endurance, and aerobic training also had no effect on cognitive performance. In one large trial, a multidomain intervention with physical activity, diet, a…