Compression Stockings to Prevent Post-Thrombotic Syndrome

In a randomized trial, individualized duration of treatment was as effective as standard-duration treatment.

The history of clinical research on compression stockings to prevent post-thrombotic syndrome after deep venous thrombosis (DVT) is convoluted. Although several small studies initially suggested benefit, the larger SOX trial, in 2013, was negative (NEJM JW Gen Med Jan 15 2014 and Lancet 2014; 383:880). Then, in 2016, the OCTAVIA study showed that 2 years of compression was more effective than 1 year (NEJM JW Gen Med Jul 15 2016 and BMJ 2016; 353:i2691). Poorer adherence to treatment in the SOX trial was one possible reason for its negative result. Now, we have the latest contribution in this sequence.

Researchers provided custom-fitted, knee-high compression stockings (ankle pressure, 30–40 mm Hg) for 865 patients with proximal DVT. After us…

Reviewing Author

Allan S. Brett, MD

Disclosures

Nothing to disclose

Allan S. Brett, MD

Disclosures

Nothing to disclose

Compression Stockings to Prevent Post-Thrombotic Syndrome

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Reviewing Author