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Studies that have demonstrated the benefit of mechanical thrombectomy (MT) for acute ischemic stroke with large vessel occlusion have relied on identification of patients with “small” infarct cores. The underlying assumption is that if there is not too much infarcted tissue at the time of treatment, there is better chance for neurologic improvement.
These authors assessed the correlations between size of the infarct core, prior to intravenous thrombolysis with or without MT, and neurologic outcomes and mortality. They identified 298 patients (median age, 67; median NIH stroke scale score, 18) enrolled in an acute-stroke trial and assessed the correlation between infarct volume on diffusion-weighted MRI and 3-month outcomes. Functional indepe…