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It has been reported that women and men suffering acute myocardial infarction (AMI) present with different symptomatology. To ascertain this in adults aged ≤55, researchers analyzed data from standardized patient interviews in the multisite VIRGO study of 2985 patients hospitalized with AMI; patients were enrolled in a 2:1 female-to-male ratio (mean age, 47; 76% white).
Chest pain, pressure, tightness, or discomfort was a presenting symptom in 87% of women and 90% of men. Overall, women presented with a greater number of additional non–chest-pain symptoms than men; 62% of women and 55% of men presented with ≥3 such symptoms. In adjusted analyses, women aged >45 had a 40% greater likelihood of presenting without chest pain than men. Women wit…