Is the Association Between Acute Pancreatitis and Pancreatic Cancer Stronger Than Presumed?

In Denmark, a 20-fold excess risk for pancreatic cancer was observed in the first 2 years after incident acute pancreatitis.

While chronic pancreatitis is an established risk factor for the development of pancreatic cancer, much less is known about the risk associated with acute pancreatitis.

In a nationwide, population-based, matched cohort study in Denmark, researchers assessed the risk for developing pancreatic cancer in over 40,000 patients hospitalized with incident acute pancreatitis and some 200,000 comparison individuals from the general population. Median follow-up was 5 years. Results were as follows:

Within the first 2 years of follow-up, patients with acute pancreatitis had a nearly 20-fold increased risk for pancreatic cancer compared with the comparison population (adjusted hazard ratio, 19.5).
The excess risk for cancer decreased over time but remaine…

Reviewing Author

Douglas G. Adler, MD, FACG, AGAF, FASGE

Disclosures

Consultant/Advisory BoardBSC; Merit; Olympus

Speaker’s BureauAbbVie

Editorial BoardsGastrointestinal Endoscopy

Douglas G. Adler, MD, FACG, AGAF, FASGE

Disclosures

Consultant/Advisory BoardBSC; Merit; Olympus

Speaker’s BureauAbbVie

Editorial BoardsGastrointestinal Endoscopy

Is the Association Between Acute Pancreatitis and Pancreatic Cancer Stronger Than Presumed?

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Reviewing Author