Incorporating Mammographic Density in a Breast Cancer Risk Assessment Tool

With or without breast density, the Tyrer-Cuzick model was equally effective in identifying high-risk women.

Currently available risk assessment tools integrate a woman's traditional risk factors (age at menarche, menopause, family history, breast biopsy pathology, and hormone replacement therapy) to calculate her lifetime risk for breast cancer. The Tyrer-Cuzick (TC) model is unique in that it also takes into account body-mass index, BRCA test results, and an extended family history that may include ovarian cancer; moreover, the latest version of this model also incorporates breast density into the risk calculation. Using Kaiser Permanente Washington breast imaging registry data from 1996 through 2013, investigators evaluated the performance of the TC model with and without breast density in a cohort study of >132,000 women (age range, 40–73) wit…

Reviewing Author

Laila Samiian, MD, FACS

Disclosures

Leadership Positions in Professional SocietiesAssociation of Women Surgeons (Member, Publications Committee)

Laila Samiian, MD, FACS

Disclosures

Leadership Positions in Professional SocietiesAssociation of Women Surgeons (Member, Publications Committee)

Incorporating Mammographic Density in a Breast Cancer Risk Assessment Tool

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Reviewing Author