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In four townships in eastern Myanmar, researchers conducted an observational study to assess providing early malaria diagnosis and treatment in all villages (population ≈365,000) and mass drug treatment in high-incidence villages. With local community involvement, they established malaria rapid diagnostic testing at >1220 community-based posts and treated infected patients with artemether-lumefantrine plus a single, low dose of primaquine. Using ultrasensitive quantitative polymerase chain reaction surveys, they identified hotspot villages: those with malaria prevalence of ≥40% and at least 20% of positives being falciparum. Hotspot residents received dihydroartemisinin-piperaquine plus single-dose primaquine monthly for 3 months and were t…