Which Stent Is Best for PCI in Saphenous Vein Grafts?

Drug-eluting stents were no better than bare metal ones in a randomized trial.

For most lesions, drug-eluting stents (DES) have proven better than bare-metal stents (BMS), due to lower rates of restenosis and repeat revascularization procedures. However, comparisons of these stents for saphenous vein graft lesions have yielded conflicting results on safety and efficacy. In a large multicenter, double-blind trial, researchers randomized 597 patients with previous coronary-artery bypass grafting to DES or BMS when undergoing percutaneous coronary interventions (PCIs) on saphenous vein grafts at 25 Veterans Affairs hospitals (NCT01121224).

Embolic protection devices were used in 69% of both groups. The DES and BMS groups showed no significant differences on the primary composite endpoint of 12-month target vessel failure …

Reviewing Author

Howard C. Herrmann, MD

Disclosures

Consultant/Advisory BoardAffluent Medical; Artedrone; Caranx; Johnson & Johnson; Medtronic; Prolifagen; Wells Fargo

EquityMicrointerventional Devices, Inc.

RoyaltiesUniversity of Pennsylvania

Grant/Research SupportAbbott Vascular; Edwards Lifesciences; Johnson & Johnson; Medtronic

Editorial BoardsCatheterization and Cardiovascular Interventions; Journal of the American College of Cardiology; Circulation: Cardiovascular Interventions; JACC Cardiovascular Interventions; JACC Case Reports; JSCAI

Leadership Positions in Professional SocietiesHeart Valve Collaboratory (Scientific Committee Member, Chair of the Publications Committee)