Five-Year Stroke Risk After Transient Ischemic Attack or Minor Stroke

In recent decades, reductions in stroke and cardiovascular events after transient ischemic attack (TIA) and minor stroke have occurred as a greater appreciation of the risk, the development of validated methods to stratify this risk, and the development and implementation of systems of care and acute interventions to modify this risk. Studies from 1997 to 2003 estimated that the 3-month risk for stroke or acute coronary syndrome after TIA or minor stroke was between 12% and 20%. But a more recent large multinational study put the 1-year risk at 6.2% (N Engl J Med 2016; 374:1533).

Now, these same investigators (TIAregistry.org) report 5-year outcomes for 3847 patients enrolled at the 42 sites where 5-year outcomes data were available for more…