qSOFA Predicts Sepsis Mortality in Low- and Middle-Income Countries

Secondary analysis of nine studies demonstrates good predictive value from quick Sequential Organ Failure Assessments in resource-limited environments.

Since the publication of Sepsis-3 (NEJM JW Gen Med Mar 15 2016 and JAMA 2016; 315:775), many investigators have compared the predictive value of the quick Sequential Organ Failure Assessment (qSOFA) with that of the Systemic Inflammatory Response Syndrome (SIRS) criteria. The studies have been conducted nearly exclusively in high-resource setting hospitals, despite the great burden of sepsis in low- and middle-income countries (LMICs).

Investigators conducted a secondary analysis of 6569 patients at risk for sepsis who were admitted to hospitals in 10 LMICs. Some trials focused on specific infections (e.g., Lassa fever, malaria), whereas others included broader populations with suspected infection. The prevalence of HIV in the study cohorts …

Reviewing Author

Patricia Kritek, MD

Disclosures

Editorial BoardsATS Scholar

Patricia Kritek, MD

Disclosures

Editorial BoardsATS Scholar

qSOFA Predicts Sepsis Mortality in Low- and Middle-Income Countries

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Reviewing Author