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The two main paralytics used for U.S. emergency department (ED) intubations are rocuronium and succinylcholine. Succinylcholine has a faster onset, but rocuronium has fewer contraindications. While previous evidence showed that succinylcholine results in better intubating conditions in the controlled environment of the operating room, it is unclear if this difference translates to the ED. This analysis of the National Emergency Airway Registry compared first-pass success rates and adverse effects in all patients older than 14 who received either paralytic as part of rapid sequence intubation in 22 EDs during 2016.
Outcomes of 4075 intubations were included; in 1800 (44%) rocuronium was used. Patients who received rocuronium were older and le…