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Data on the diagnosis and prognosis of acute myocarditis are relatively thin; recommendations regarding diagnostic tests such as endomyocardial biopsy and cardiac magnetic resonance (CMR) are not emphatic. Furthermore, data on progression of left ventricular systolic dysfunction or to symptomatic heart failure are based on relatively small studies from tertiary-referral facilities, which can result in biased and pessimistic estimates, as seen with hypertrophic cardiomyopathy. To learn more, researchers in Italy analyzed data on 443 patients aged <70 (median age, 34; 19% women, median left ventricular ejection fraction [LVEF], 55%) with suspected acute myocarditis admitted to hospitals within 30 days of symptom onset between 2001 and 2017.
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