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Interventions to improve medication adherence often are labor-intensive and expensive. In this study, researchers recruited 2038 adults with poorly controlled hypertension, hyperlipidemia, or diabetes to assess a multicomponent, non–face-to-face intervention. Fourteen Massachusetts primary care practices were randomized to usual care or to an intervention based on telephone interviewing by a clinical pharmacist to identify individual behavioral barriers to adherence. Intervention patients received tailored, mailed consultation reports (as did their primary care physicians), text message reminders, and medication-reminder electronic pillboxes. Adherence was assessed with pharmacy claims data during 12 months of follow-up.
The two most common …