In a randomized trial, a flexible integrated intervention directed to people who inject drugs increased antiretroviral and medication-assisted therapy use and reduced mortality.
Persons living with HIV who inject drugs have lower rates of engagement in care and higher mortality. With a growing epidemic of HIV infection among persons who inject drugs (PWID) in Central and Eastern Europe and Southeast Asia there is an urgent need to develop interventions that increase antiretroviral therapy (ART) and medication-assisted therapy (MAT).
HPTN 074, a randomized, controlled trial conducted in Eastern Europe (Ukraine) and Southeast Asia (Vietnam and Indonesia), compared standard-of-care treatment with a flexible, integrated intervention to facilitate initiation of ART and MAT use among PWID. The intervention consisted of help with navigating the country's medical system, psychological support, and ART regardless of CD4 coun…
Reviewing Author
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)
DisclosuresGrant/Research SupportNIH/National Institute of Allergy and Infectious Diseases; NIH/National Institute on Drug Abuse
Editorial BoardsJAIDS: Journal of Acquired Immune Deficiency Syndromes; Vaccines
Leadership Positions in Professional SocietiesInternational Antiviral Society–USA (Board of Directors); Infectious Diseases Society of America (Past President)