Pregnancy Rates in Multiple Sclerosis Increasing Over Time

Researchers retrospectively studied pregnancy rates, complications, and outcomes in women with and without multiple sclerosis (MS) using the 2006 to 2015 IQVIA Real World Data Adjudicated Claims — U.S. database, which represents commercially insured individuals generally younger than 65. The annual number of women with MS included through 2014 ranged from 36,361 to 58,218. Of 2176 patients with MS who had a live birth plus follow-up for at least 1 year pre- and postpregnancy, 2115 women with MS were propensity score matched 1:1 to women without MS for age, region, payer, and comorbidities.

Overall, the mean age of pregnancy was higher for those with MS than for those without MS (32.5 vs. 29.3 years). Over time, the adjusted pregnancy rate fl…