Epidemiology and Costs of Sepsis in the U.S.

Sepsis, severe sepsis, and septic shock were associated with 6%, 15%, and 34% mortality rates and costs of approximately $16,000, $25,000, and $38,000, respectively, in a large retrospective database analysis.

Sepsis incidence in the U.S. has increased annually by 8% to 9% during the past two decades, with considerable economic impact (13% of total U.S. hospital costs) and high associated mortality. Researchers conducted a retrospective observational study using a commercial database representing approximately 20% of U.S. inpatient admissions to characterize the clinical features of sepsis associated strongly with healthcare utilization, focusing especially on timing of sepsis diagnosis.

The analysis involved 2,466,605 sepsis cases treated as inpatients between January 2010 and September 2016, out of 2,566,689 total sepsis cases (mean age, 65 years; 50.8% female). Of these, 54.6%, 16.7%, and 21.0% had sepsis without organ dysfunction, severe sepsi…

Reviewing Author

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Thomas Glück, MD

Disclosures

Editorial BoardsConsilium Infectiorum by InfectoPharm, Infection

Epidemiology and Costs of Sepsis in the U.S.

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Reviewing Author