The combination of cardiac injury and malignant left ventricular hypertrophy strongly increased the risk for heart failure in black people in the U.S.
African-Americans have a high risk for heart failure (HF), and it would be useful to identify people at the greatest risk. To determine whether left ventricular hypertrophy (LVH) and subclinical myocardial injury are associated with heightened HF risk, investigators made use of data on 3987 community-dwelling African-American adults (median age, 54) participating in the Jackson Heart Study, a prospective, observational cohort study.
At baseline clinical examinations, participants underwent high-sensitivity cardiac troponin-I (hs-cTnI) testing and echocardiography. HF hospitalization, the primary outcome, was identified from annual interviews and review of hospital discharge lists and was confirmed with adjudication.
The prevalence of LVH was …
Reviewing Author
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association
DisclosuresConsultant/Advisory BoardUnited Healthcare; Element Science; Eyedentifeye, F-Prime
EquityHugo Health; Refactor Health; Element Science
Grant/Research SupportPfizer; Agency for Healthcare Research and Quality; Janssen Research and Development, National Institute of Biomedical Imaging and Engineering; National Heart, Lung, and Blood Institute; Centers for Disease Control and Prevention; National Cancer Institute; American Heart Association